Officers, along with Guelph Wellington Paramedics and local fire departments responded around 8:30 am on a report of an injured cyclist on Wellington Road 2 at Regency Drive in Minto Township.
It was determined they had been struck by a vehicle that did not remain at the scene of the collision.
The cyclist, a 21-year-old from Clifford was transported to a trauma centre by Air Ornge with serious injuries.
As a result of the investigation a 28-year-old female of West Grey Township has charges that include failing to remain at an accident resulting in bodily injury, careless driving causing injury, and failing to report an accident.